C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
150/15, 260/227,
C07K 2/00 (2006.01) C09B 23/01 (2006.01) C09B 23/10 (2006.01) C09B 23/14 (2006.01) C12Q 1/00 (2006.01) C12Q 1/34 (2006.01)
Patent
CA 2000596
Chromogenic merocyanine enzyme substrate compounds of the general formula: (see formula I) where Y is an enzymatically-cleavable group such as a radical of a sugar, carboxylic acid, amino acid, peptide, phosphoric acid, or sulfuric acid; A and B represent residues that complete 5- or 6-membered ring systems; R1 is substituted or unsubstituted alkyl; R2 and R3, independently, are hydrogen or lower alkyl; m, n, and p, which can be different, are intergers from 0 through 3 provided that m + n + p must be at least 2; and x is an appropriate counterion (anion). These components are useful as optical indicator compounds in analytical test systems for example for the detection of enzymes in a liquid test sample.
Corey Paul F.
Yip M. Teresa
Corporation Bayer
Osler Hoskin & Harcourt Llp
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