Chromogenic thrombin substrates

C - Chemistry – Metallurgy – 12 – Q

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150/15, 530/5.08

C12Q 1/56 (2006.01) C07K 1/06 (2006.01) C07K 5/087 (2006.01)

Patent

CA 1068261

Abstract of the Disclosure Novel diagnostically active chromogenic substrates with a high specificity for thrombin and thrombin-like enzymes, characterized by the fact that they have the general formula Image and salts thereof, wherein R1 is hydrogen or hydroxy, R2 is nitrophenyl, naphthyl or methoxynaphthyl, n is 1, 2 or 3, and * indicates the D-configura- tion.

256417

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