Chromone derivative, process for preparing same and...

C - Chemistry – Metallurgy – 07 – D

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C07D 405/04 (2006.01) A61K 31/35 (2006.01) A61K 31/38 (2006.01) C07D 409/04 (2006.01)

Patent

CA 2182932

A chromone derivative of the formula (I): Image (I) wherein R11 is a pyrazolyl, pyrrolyl, triazolyl, benzotriazolyl, benz-imidazolyl, indazolyl, or indolyl group, R2, R3, R4, and R5 is independently a hydrogen or halogen atom, or a hydroxy or alkoxy group, or an alkoxy group substituted with one or more alkoxy groups, and X is an oxygen or sulfur atom, or a salt thereof is disclosed. The chromone derivative inhibits the activity of matrix metalloproteinase.

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