Chromophore containing compounds and their use in...

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/37 (2006.01) C07K 5/08 (2006.01) C07K 5/10 (2006.01) C07K 5/107 (2006.01) C07K 7/06 (2006.01) C07K 7/08 (2006.01) C07K 14/545 (2006.01)

Patent

CA 2075662

218/CCP100 219/CCP101 18516IA TITLE OF THE INVENTION NOVEL CHROMOPHORE CONTAINING COMPOUNDS AND THEIR USE IN DETERMINING INTERLEUKIN-1.beta. CONVERTASE ACTIVITY. ABSTRACT OF THE INVENTION Disclosed are novel chromophore containing compounds of Formula II and their use in determining interleukin-1.beta. convertase (ICE) activity. ICE has been implicated in inflammatory or immune-based diseases of the lung and airways; central nervous system and surrounding membranes; the eyes and ears; joints, bones, and connective tissues; cardiovascular system including the pericardium; the gastrointestinal and urogenital systems; the skin and mucosal membranes. Image II

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