C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/37 (2006.01) C07K 5/08 (2006.01) C07K 5/10 (2006.01) C07K 5/107 (2006.01) C07K 7/06 (2006.01) C07K 7/08 (2006.01) C07K 14/545 (2006.01)
Patent
CA 2075662
218/CCP100 219/CCP101 18516IA TITLE OF THE INVENTION NOVEL CHROMOPHORE CONTAINING COMPOUNDS AND THEIR USE IN DETERMINING INTERLEUKIN-1.beta. CONVERTASE ACTIVITY. ABSTRACT OF THE INVENTION Disclosed are novel chromophore containing compounds of Formula II and their use in determining interleukin-1.beta. convertase (ICE) activity. ICE has been implicated in inflammatory or immune-based diseases of the lung and airways; central nervous system and surrounding membranes; the eyes and ears; joints, bones, and connective tissues; cardiovascular system including the pericardium; the gastrointestinal and urogenital systems; the skin and mucosal membranes. Image II
Chapman Kevin T.
Maccoss Malcolm
Mumford Richard A.
Thornberry Nancy A.
Weidner Jeffrey R.
Chapman Kevin T.
Gowling Lafleur Henderson Llp
Maccoss Malcolm
Merck & Co. Inc.
Mumford Richard A.
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