C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/37 (2006.01) C07K 5/08 (2006.01) C07K 5/10 (2006.01) C07K 5/107 (2006.01) C07K 7/06 (2006.01) C07K 7/08 (2006.01) C07K 14/545 (2006.01)
Patent
CA 2075685
218/CCP100 219/CCP101 18517Y TITLE OF THE INVENTION NOVEL CHROMOPHORE CONTAINING COMPOUNDS AND THEIR USE IN DETERMINING INTERLEUKIN-1.beta. CONVERTASE ACTIVTY. ABSTRACT OF THE INVENTION Disclosed are novel chromophore containing compounds of Formula I and their use in determining interleukin-1.beta. convertase (ICE) activity. ICE has been implicated in inflammatory or immune-based diseases of the lung and airways; central nervous system and surrounding membranes; the eyes and ears; joints, bones, and connective tissues; cardiovascular system including the pericardium; the gastrointestinal and urogenital systems; the skin and mucosal membranes. Image I
Chapman Kevin T.
Hagmann William K.
Maccoss Malcolm
Mumford Richard A.
Thornberry Nancy A.
Chapman Kevin T.
Gowling Lafleur Henderson Llp
Hagmann William K.
Maccoss Malcolm
Merck & Co. Inc.
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