Chromosome-based platforms

Details Chromosome-based platforms Chromosome-based platforms

C - Chemistry, Metallurgy

12

N

C12N 15/79 (2006.01) A01K 67/02 (2006.01) C07H 21/00 (2006.01) C07K 14/00 (2006.01) C07K 14/435 (2006.01) C12N 5/00 (2006.01) C12N 9/22 (2006.01) C12N 15/09 (2006.01) C12N 15/11 (2006.01) C12N 15/63 (2006.01) C12N 15/66 (2006.01) C12N 15/82 (2006.01) C12N 15/85 (2006.01) C12N 15/87 (2006.01) C12N 15/90 (2006.01) C12Q 1/00 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2441937

Artificial chromosomes, including Aces, that have been engineered to contain available sites for site-specific, recombination-directed integration of DNA of interest are provided. These artificial chromosomes permit tractable, efficient, rational engineering of the chromosome for a variety of applications.

L'invention concerne des chromosomes artificiels, comprenant Aces, qui ont été modifiés génétiquement pour contenir des sites disponibles destinés à une intégration recombinante dirigée d'un ADN d'intérêt. Ces chromosomes artificiels permettent une modification génétique résoluble, efficiente et rationnelle du chromosome pour diverses applications.

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