Chromosome detector using a scanning microscope system

G - Physics – 01 – N

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G01N 21/27 (2006.01) G01J 1/20 (2006.01) G01N 15/14 (2006.01)

Patent

CA 1136887

Case 04-4215-U.S. APPLICATION OF GERRY D. HUNTER AND GASTON A. PALOMBO CHROMOSOME DETECTOR USING A SCANNING MICROSCOPE SYSTEM ABSTRACT A chromosome detector using a scanning microscope system is used to detect the presence of a chromosome spread in a slide specimen and to produce a signal usable by the scanning microscope system to automatically operate the microscope system whereby the detected chromosomes are centered in the field of view, are automatically focused and their location converted to coordinate data which is stored in a memory system whereby the system may be used to re-examine the detected chromosome by the use of the stored X-Y coordinates. The detector performs an amplitide and frequency analysis of a cell find signal produced by a slide scanner in the scanning microscope system and produces, in turn, an output signal representative of a detected chromosome spread and compatible with the scanning microscope control circuit.

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