Chronic, bolus administration of d-threo methylphenidate

Details Chronic, bolus administration of d-threo methylphenidate Chronic, bolus administration of d-threo methylphenidate

A - Human Necessities

61

K

A61K 31/445 (2006.01) A61K 31/4458 (2006.01)

Patent

CA 2241611

Chronic bolus administration of D-threo methylphenidate is provided. The administration of the D-threo isomer eliminates adverse side effects associated with the DL racemate, and provides improved effectiveness. The compositions and methods of the invention are useful in treating nervous system disorders including attention deficit disorder, attention deficit hyperactivity disorder, and cognitive decline associated with systemic diseases such as acquired immunodeficiency syndrome.

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