Chymotrypsin for the inactivation of prekallikrein activator

Details Chymotrypsin for the inactivation of prekallikrein activator Chymotrypsin for the inactivation of prekallikrein activator

C - Chemistry, Metallurgy

12

S

167/114, 167/139

C12S 3/22 (2006.01) A61K 35/16 (2006.01) A61K 38/38 (2006.01) A61K 39/395 (2006.01) C07K 1/14 (2006.01) C07K 14/76 (2006.01) C07K 16/00 (2006.01) C07K 16/06 (2006.01) C12P 21/06 (2006.01)

Patent

CA 1338499

In order to avoid the risk of undesired side reactions of blood products, the latter are produced from plasma by using chymotrypsin to inactivate prekallikrein activator. These preparations are obtained by the fractionated enrichment of plasma proteins, with the proviso that a chymotrypsin solution or immobilized chymotrypsin is added to the fractions at any stage of the fractionation process. Before completion of the preparations, the chymotrypsin or the immobilized trypsin is removed from the preparations.

591730

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