A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/415 (2006.01) A61K 9/20 (2006.01) A61K 31/475 (2006.01) A61K 47/04 (2006.01) A61K 47/12 (2006.01)
Patent
CA 2244389
Solid and liquid pharmaceutical preparations containing cilansetron or its acid addition salts as active substance which include an amount sufficient to stabilize cilansetron against racemization, of a physiologically compatible water-soluble acid additive selected from monobasic or multibasic organic acids having 2 to 12 carbon atoms with a first pK s value between 1.1 and 4.8, acid salts of the aforementioned multibasic organic acids, and acid salts of multibasic mineral acids having a first available pK s value between 1.5 and 7.5, as well as the use of such acid additives for stabilizing cilansetron against racemization in pharmaceutical preparations.
Bonnacker Ingo
Koehn Hartmut
Kristen Gerhard
Reichel Christine
Mccarthy Tetrault Llp
Solvay Pharmaceuticals Gmbh
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