C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 409/12 (2006.01) A61K 31/40 (2006.01) A61K 31/4025 (2006.01) A61P 31/04 (2006.01) C07D 207/40 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01) C07D 405/12 (2006.01) C07D 405/14 (2006.01)
Patent
CA 2483303
The present invention relates to compounds of Formula (I), to processes for preparing them, to pharmaceutical compositions comprising them, and to their use in the therapy and/or prophylaxis in illnesses in people or animals, especially diseases of bacterial infection, (see formula I) in which R1 is hydrogen, methyl or halogen; R1' is hydrogen, methyl or halogen; R2 is hydrogen or methyl; R3 is hydrogen, hydroxyl etc; R4 is hydrogen or C1-C3 alkyl, R5 is halogen, trifluoromethyl etc; or two substituents R5 together with the carbon atoms to which they are attached form a cycloalkyl or heterocyclyl each of which may be substituted; R6 is alkyl, cycloalkyl or cycloalkenyl; it being possible for R6 to be substituted; n is a number 0, 1, 2 or 3; m is a number 1, 2 or 3; A is aryl or heteroaryl; it being possible for A to be substituted; or two substituents R A together with the carbon atoms to which they are attached form a cycloalkyl or heterocyclyl each of which may be substituted; and B is aryl or heteroaryl.
La présente invention concerne des composés, leurs procédés de production, les compositions pharmaceutiques les contenant et leur utilisation pour traiter et/ou prévenir des maladies, notamment des maladies infectieuses bactériennes, chez les hommes ou les animaux.
Brunner Nina
Endermann Rainer
Freiberg Christoph
Lampe Thomas
Nell Peter
Bayer Healthcare Ag
Fetherstonhaugh & Co.
Intermed Discovery Gmbh
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