Cinnamic acid derivatives and their use as integrin antagonists

Details Cinnamic acid derivatives and their use as integrin antagonists Cinnamic acid derivatives and their use as integrin antagonists

C - Chemistry, Metallurgy

07

C

C07C 279/18 (2006.01) A61K 31/19 (2006.01) A61K 31/21 (2006.01) A61K 31/33 (2006.01) A61K 31/41 (2006.01) A61K 31/44 (2006.01) A61K 31/505 (2006.01) A61K 31/535 (2006.01) C07C 205/34 (2006.01) C07C 205/35 (2006.01) C07C 205/37 (2006.01) C07C 205/44 (2006.01) C07C 205/45 (2006.01) C07C 205/56 (2006.01) C07C 275/42 (2006.01) C07C 279/22 (2006.01) C07C 279/24 (2006.01) C07C 311/45 (2006.01) C07C 335/22 (2006.01) C07D 231/06 (2006.01) C07D 233/50 (2006.01) C07D 233/54 (2006.01) C07D 233/64 (2006.01) C07D 233/88

Patent

CA 2250690

The present invention relates to a class of compounds represented by formula (I) or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising compounds of formula (I), and methods of selectively inhibiting or antagonizing the .alpha.v.beta.3 integrin.

La présente invention se rapporte à une classe de composés représentés par la formule (I), ou à un sel pharmaceutiquement acceptable de ceux-ci, à des compositions pharmaceutiques comprenant les composés de la formule (I), et à des procédés visant à inhiber ou antagoniser l'intégrine .alpha.¿v?.beta.¿3?.

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