Cinnamic acid derivatives, their preparation, and...

Details Cinnamic acid derivatives, their preparation, and... Cinnamic acid derivatives, their preparation, and...

C - Chemistry, Metallurgy

07

D

260/552, 260/515

C07D 317/26 (2006.01) C07C 205/56 (2006.01)

Patent

CA 1153010

- ABSTRACT - A compound of the formula Image or a pharmaceutically acceptable ester, amide or salt thereof wherein R1 is a hydrogen, fluorine, chlorine or bromine atom or a hydroxyl, hydroxymethyl, methyl, methoxyl, amino, formamido, acetamido, methylsulphonylamido, nitro, benzyloxy, methyl- sulphonylmethyl, ureido, trifluoromethyl or p-methoxybenzylamino group; R2 is a hydrogen, fluorine, chlorine or bromine atom or a hydroxyl group; R3 is a hydrogen, chlorine or bromine atom or a hydroxyl group; R4 is a hydrogen, chlorine or fluorine atom or a methyl, methoxyl or hydroxyl group or a carboxylic acid group or a salt, ester or amide thereof; R5 is a hydrogen atom or a methyl group; R6 is a hydrogen atom or a methyl group; R7 is a hydrogen atom or a methyl or ethyl group; R8 is a hydrogen atom or a methyl or ethyl group; X is an oxygen atom or a bond, and Y is an alkylene group of up to 5 carbon atoms, or a bond has been found to possess anti-obesity and/or anti-hyper- glycaemic activity.

359622

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