Cinnamic acid dimers, their preparation and the use thereof...

Details Cinnamic acid dimers, their preparation and the use thereof... Cinnamic acid dimers, their preparation and the use thereof...

A - Human Necessities

61

K

A61K 31/194 (2006.01) A61P 25/28 (2006.01) C07C 59/68 (2006.01)

Patent

CA 2487165

The present invention relates to cinnamic acid dimers, their preparation and the use thereof for treating neurodegenerative disease, which have excellent effect on enhancing the learning and memory-retention ability in vivo and have fewer side-effects by showing no hormone properties, even when administered for a long period of time, and thus which can be used for neurodegenerative disease including dementia.

L'invention porte sur des dimères d'acide cinamique, leur préparation et leur utilisation dans le traitement des maladies neurodégénératives. Ces dimères possèdent un excellent effet sur l'amélioration de la capacité d'apprentissage et de mémorisation in vivo et présentent moins d'effets secondaires du fait qu'elles n'ont pas de propriétés hormonales, même lorsqu'elles sont administrées pendant une longue durée, et, par conséquent, peuvent être utilisées pour traiter des maladies neurodégénératives telles que la démence.

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