Cinnamoylpiperidinobutyrophenone antipsychotic agents

Details Cinnamoylpiperidinobutyrophenone antipsychotic agents Cinnamoylpiperidinobutyrophenone antipsychotic agents

C - Chemistry, Metallurgy

07

D

260/292.2

C07D 211/32 (2006.01) C07D 211/62 (2006.01)

Patent

CA 1147734

M-1043 ABSTRACT OF THE DISCLOSURE Cinnamoylpiperidinobutyrophenone derivatives and pharmaceutically acceptable salts thereof of the following general structure: Image wherein R is hydrogen, alkyl, alkoxy, halogen or trifluoromethyl; and R' is hydrogen or halogen; are useful as antipsychotic agents. The novel compounds are produced by aldol condensation of a benzaldehyde with a protected 4-(4-acetyl-1-piperidino)-butyrophenone.

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