Cinnamylidene camphor derivatives and their use as uv-a...

Details Cinnamylidene camphor derivatives and their use as uv-a... Cinnamylidene camphor derivatives and their use as uv-a...

C - Chemistry, Metallurgy

07

C

C07C 225/22 (2006.01) A61K 8/35 (2006.01) A61K 31/125 (2006.01) A61K 31/135 (2006.01) A61Q 17/04 (2006.01) C07C 45/51 (2006.01) C07C 45/74 (2006.01) C07C 49/683 (2006.01) C07C 49/697 (2006.01) C07C 49/753 (2006.01) C09K 15/06 (2006.01)

Patent

CA 2248165

The invention relates to cinnamylidene camphor derivatives of the formula (1) in which the diene system is in the configuration Z,Z; Z,E; E,Z or E, E and R1 is H, CH3, R2 is C1-C6 alkyl, C1-C6 alkoxy, halogen, NR3H, NR32, R3 is C1-C4 alkyl, R4 is H, C1-C6 alkyl, and n is 1, 2, and their use as UV-A protecting agents, especially in cosmetical and pharmaceutical formulations.

L'invention concerne des dérivés du cinnamylidène-camphre, de formule (1), où le système diène se présente sous la configuration Z,Z; Z,E; E,Z ou E,E; et où R?1¿ est H ou CH¿3?; R?2¿ est alkyle C¿1?-C¿6?, alcoxy C¿1?-C¿6?, halogène, NR?3¿H ou NR?3¿¿2?; R?3¿ est alkyle C¿1?-C¿4?; R?4¿ est H ou alkyle C¿1?-C¿6?; n est 1 ou 2; ainsi que leur utilisation en tant qu'agents de protection contre les UV-A, notamment dans des formulations cosmétiques et pharmaceutiques.

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