Cinnoline compounds and their use as liver x receptor...

Details Cinnoline compounds and their use as liver x receptor... Cinnoline compounds and their use as liver x receptor...

C - Chemistry, Metallurgy

07

D

C07D 237/28 (2006.01) A61K 31/502 (2006.01) A61P 3/10 (2006.01) A61P 9/00 (2006.01) A61P 25/28 (2006.01) A61P 29/00 (2006.01) C07D 403/12 (2006.01) C07D 409/12 (2006.01)

Patent

CA 2599688

This invention relates to cinnoline-based modulators of Liver X receptors (LXRs) of formula (I) wherein R2 is a ring containing residue, particularly a phenyl residue. These compounds are useful in the treatment of cardiovascular diseases.

La présente invention a trait à des modulateurs des récepteurs hépatiques X (LXR) de formule (1) où R2 est un anneau contenant un résidu, notamment un résidu phénylique. Ces composés servent au traitement des maladies cardio-vasculaires.

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