Circulating antigens of dirofilaria immitis, monoclonal...

A - Human Necessities – 61 – K

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167/129, 167/37,

A61K 39/395 (2006.01) A61K 39/00 (2006.01) C12N 5/00 (2006.01) C12N 15/00 (2006.01) G01N 33/577 (2006.01)

Patent

CA 1232849

Abstract of the Disclosure Novel hybrid cell lines are disclosed for providing monoclonal antibodies to circulating parasite antigens present in the blood of animals infected with the nematode parasite Dirofilaria immitis. Such circulating parasite antigens are also characterized and identified. Further disclosed are methods employed to produce and select such hybrid cell lines and diagnostically useful assay methods utilizing the mono- clonal antibodies in the detection of such specific circulat- ing parasite antigens in blood or bodily fluids.

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