Circulating tumor cell assay

G - Physics – 01 – N

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G01N 33/574 (2006.01) G01N 33/50 (2006.01)

Patent

CA 2653745

Methods for the detection, enumeration and analysis of circulating tumor cells expressing insulin-like growth factor-1 receptors (IGF-1R) are disclosed. These methods are useful for cancer screening and staging, development of treatment regimens, and for monitoring for treatment responses, cancer recurrence or the like. Test kits that facilitate the detection, enumeration and analysis of such circulating tumor cells are also provided.

La présente invention concerne des procédés de détection, d'énumération et d'analyse de cellules tumorales circulantes qui expriment les récepteurs 1 du facteur de croissance de type insuline (IGF-1R). Ces procédés se révèlent utiles pour le criblage et la détermination du stade d'un cancer, le développement de régimes de traitement, et le suivi des réponses au traitement, de la récurrence du cancer, ou d'éléments analogues. La présente invention concerne également des trousses de test qui facilitent la détection, l'énumération et l'analyse desdites cellules tumorales circulantes.

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