C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
195/1.2, 195/1.2
C12N 15/85 (2006.01) C07K 14/61 (2006.01) C12N 15/11 (2006.01)
Patent
CA 1339733
Cis-acting repression sequences which are able to provide a cis-acting inhibitory effect on the expression of a gene when placed downstream of the gene in its untranslated message are dislcosed. Cis-acting anti-repression sequences which can relieve the cis-acting repression in the presence of the art gene product are also disclosed. These sequences correspond to a sufficient number of nucleotides from the HIV-I, HIV-2, STLV-3 or HTLV-IV genomes to provide the repression or anti-repression effects. The use of the sequences in vectors and systems to control the expression of a desired gene product is also described. . . . .
567929
Haseltine William A.
Rosen Craig A.
Sodroski Joseph G.
Terwilliger Ernest
Dana Farber Cancer Institute
Ridout & Maybee Llp
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