Cis-diammineplatinum(ii) orthophosphate complexes

C - Chemistry – Metallurgy – 01 – B

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167/292, 23/65

C01B 25/37 (2006.01) A61K 33/42 (2006.01) C01B 21/097 (2006.01)

Patent

CA 1128285

Abstract Cis-diammineplatinum(II) orthophosphate complexes are prepared by reaction of diaquo-cis-diammineplatinum(II) salts with alkali metal orthophosphates. The resulting complexes possess pronounced anti-tumor activity and low toxicity; consequently, they have high therapeutic indices.

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