Clausenamide c5 hydroxyl derivatives and n-substituted...

C - Chemistry – Metallurgy – 07 – D

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C07D 207/273 (2006.01) A61K 31/40 (2006.01) A61P 43/00 (2006.01)

Patent

CA 2512205

The invention provides C5 hydroxyl substituted clausenamide stereoisomer , N- substituted Derivatives and processes for their preparation, it also provides its pharmaceutical composition containing the same compounds as the active components and the use in the preparation of a medicament for the treatment of senilism and for improving memory.

L'invention se rapporte à des stéréoisomères de clausénamide à substitution C¿5?-hydroxyle, à des dérivés N-substitués et à des procédés de préparation de ces dérivés. L'invention se rapporte également à une composition pharmaceutique contenant les mêmes composés que ces composés actifs, et à l'utilisation de ces dérivés pour la préparation d'un médicament permettant le traitement de la sénilité et l'amélioration de la mémoire.

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