Clavulanic acid esters

Details Clavulanic acid esters Clavulanic acid esters

C - Chemistry, Metallurgy

07

D

260/299

C07D 498/04 (2006.01)

Patent

CA 1076120

ABSTRACT OF THE DISCLOSURE A new antibacterially active agent has been isolated from Streptomyces clavuligerus. This new compound which we designate clavulanic acid has the formula (I): Image (I) In addition to being a broad spectrum antibiotic of medium potency, clavulanic acid and its salts and esters have the ability to enhance the effectiveness of .beta.-lactam antibiotics against many .beta.-lactamase producing bacteria.

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