Clavulanic acid from streptomyces clavuligerus

Details Clavulanic acid from streptomyces clavuligerus Clavulanic acid from streptomyces clavuligerus

C - Chemistry, Metallurgy

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C12P 19/44 (2006.01) A61K 31/00 (2006.01) A61K 31/42 (2006.01) A61K 31/43 (2006.01) C07D 503/00 (2006.01) C12P 17/18 (2006.01)

Patent

CA 1059050

ABSTRACT OF THE DISCLOSURE A new antibacterially active agent has been isolated from Streptomyces clavuligerus. This new compound which we designate clavulanic acid has the formula (I): Image (I) In addition to being a broad spectrum antibiotic of medium potency, clavulanic acid and its salts and esters have the ability to enhance the effectiveness of .beta.-lactam antibiotics against many .beta.-lactamase producing bacteria.

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