Clindamycin phosphate foam

A - Human Necessities – 61 – K

Patent

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Details

IPC codes

A61K 31/4025 (2006.01) A61K 8/04 (2006.01) A61K 9/12 (2006.01) A61K 45/06 (2006.01) A61P 17/10 (2006.01)

Type

Patent

Patent number

CA 2513773

Description

The present invention provides various pharmaceutically active topical delivery compositions. In particular, compositions of the present invention are present in a pressurized container comprising a quick-breaking alcoholic foaming agent, such that when the composition is released, i.e., dispensed, from the pressurized container, a quick-breaking temperature sensitive foam is formed. In addition, the present invention provides various aspects related to such compositions, including methods for modulating a foam characteristic, methods for improving the shelf-life of a pharmaceutically active compound, methods for the percutaneous treatment of various diseases, infections, and illnesses, and methods for evaluating foam characteristics.

La présente invention concerne différentes compositions de délivrance topique ayant une action pharmaceutique. Les compositions selon l'invention sont notamment contenues dans un contenant sous pression comportant un agent moussant alcoolique à rupture rapide de telle façon que lorsque la composition est libérée, notamment distribuée, à partir du contenant sous pression, il se forme une mousse sensible à la température à rupture rapide En plus, la présent invention concerne différents aspects liés à de telles compositions, y compris des procédés de modulation d'une caractéristique de la mousse, des procédés permettant d'améliorer durée de conservation d'un composé pharmaceutiquement actif, des procédés de traitement percutané de différentes maladies et infections et des procédés d'évaluation des caractéristiques de la mousse.

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