Clioquinol for the treatment of hematological malignancies

A - Human Necessities – 61 – K

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A61K 31/47 (2006.01) A61K 33/34 (2006.01) A61P 35/00 (2006.01) A61P 35/02 (2006.01)

Patent

CA 2702805

The present invention relates to compositions and methods for treating hematological malignancies and proliferative diseases, disorders and conditions involving increased D-cyclin expression. In particular, the present invention relates to composi-tions and methods for treating the hematological malignancies acute myeloid leukemia (AML) and multiple myeloma (MM) using clioquinol.

La présente invention concerne des compositions et des procédés destinés à traiter des malignités hématologiques, des maladies prolifératives, des troubles et des états impliquant une augmentation de l'expression de la cycline D. En particulier, la présente invention concerne des compositions et des procédés destinés à traiter les malignités hématologiques telles que la leucémie myéloïde aiguë et le myélome multiple au moyen de clioquinol.

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