A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
167/256
A61K 9/14 (2006.01) A61K 9/20 (2006.01) A61K 31/66 (2006.01)
Patent
CA 1298196
ABSTRACT Clodronate-containing medicaments and a process for the preparation thereof The present invention provides a medicament containing 80 to 95% clodronate, 2 to 10% filling material and 1 to 10% lubricant. The present invention also provides a process for the production of a clodronate-containing medicament containing 80 to 95% clodronate, 2 to 10% filling material and 1 to 10% lubricant, wherein the dry components are mixed, moist granulated with an aqueous binding agent and the granulate obtained subsequently dried, a lubricant being additionally admixed with the final granulate in an amount of from 1 to 5% and the mixture thus obtained pressed into tablets or filled into capsules which have a rate of dissolving of > 90% after 30 minutes.
554722
Demmer Fritz
Stemmle Berthold
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
Roche Diagnostics Gmbh
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