Clonal myeloma cell lines useful for manufacturing proteins...

C - Chemistry – Metallurgy – 12 – N

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Details

C12N 5/10 (2006.01) C12N 5/09 (2010.01) C07K 14/00 (2006.01) C07K 16/00 (2006.01) C12N 15/87 (2006.01) C12P 21/02 (2006.01) C12Q 1/02 (2006.01)

Patent

CA 2470026

The present invention relates to clonal myeloma cell lines that have the ability to grow continuously in chemically defined media. The present invention also relates to the production of proteins in clonal myeloma cell lines and any cell lines derived therefrom. The present invention further relates to methods for identifying cell lines capable of growing in chemically defined media. The present invention also relates to business methods where customers are provided with the cells, cell lines, and cell cultures of the present invention.

L'invention porte: sur des lignées de cellules clonales de myélomes pouvant croître continuellement dans un milieu défini chimiquement; sur la production de protéines dans des lignées cellules clonales de myélomes et toute lignée en dérivant; sur des procédés d'identification de lignées de cellules pouvant croître dans un milieu défini chimiquement; et sur des méthodes commerciales permettant de fournir à des clients les cellules, lignées de cellules et cultures de cellules de la présente invention.

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