Clonal propagation of primate offspring by embryo splitting

Details Clonal propagation of primate offspring by embryo splitting Clonal propagation of primate offspring by embryo splitting

A - Human Necessities

01

K

A01K 67/027 (2006.01) C12N 5/06 (2006.01) C12N 15/87 (2006.01) G01N 33/48 (2006.01)

Patent

CA 2396247

The present invention relates to the clonal propagation of primate offspring by embryo splitting. Here, genetically identical nonhuman embryos may be produced as twin and larger sets by separation and reaggregation of blastomeres of cleavage-stage embryos. Furthermore, the present invention also relates to methods for producing embryonic stem cells and transgenic embryonic stem cells isolated from dissociated blastomeres.

La présente invention concerne la propagation clonale de descendance de primates par sectionnement d'embryons. Des embryons non humains génétiquement identiques peuvent être produits sous forme de jumeaux ou d'ensembles plus importants par séparation et réagrégation de blastomères d'embryons au stade de la division. Cette invention concerne aussi des techniques de production de cellules embryonnaires et de cellules embryonnaires transgéniques isolées de blastomères dissociées.

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