C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
195/122, 530/13,
C12N 15/62 (2006.01) A61K 47/48 (2006.01) A61K 49/00 (2006.01) A61K 51/08 (2006.01) C07K 14/73 (2006.01) C07K 16/00 (2006.01) C07K 19/00 (2006.01) C12N 15/12 (2006.01) C12N 15/13 (2006.01) G01N 33/569 (2006.01)
Patent
CA 1340741
The invention relates to a fusion protein which comprises an immunoglobulin of the IgM, IgG1 or IgG3 immunoglobulin class, wherein the variable region of the light or heavy chain has been replaced with CD4 or fragment thereof which is capable of binding to gp120. The invention also relates to an immunoglobulin-like molecule comprising the fusion protein of the invention together with an immunoglobulin light or heavy chain. The invention also relates to a method of treating HIV or SIV infection comprising administering the fusion proteins or immunoglobulin-like molecules of the invention to an animal. The invention also relates to assays for HIV or SIV comprising contacting a sample suspected of containing HIV or SIV gp120 with the immunoglobulin-like molecule of fusion protein of the invention, and detecting whether a complex is formed.
588749
Seed Brian
Gowling Lafleur Henderson Llp
Seed Brian
The General Hospital Corporation
LandOfFree
Cloned genes encoding ig-cd4 fusion protiens and the use... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Cloned genes encoding ig-cd4 fusion protiens and the use..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Cloned genes encoding ig-cd4 fusion protiens and the use... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1296902