Cloned leptospira outer membrane protein

Details Cloned leptospira outer membrane protein Cloned leptospira outer membrane protein

C - Chemistry, Metallurgy

12

N

C12N 15/31 (2006.01) A61K 39/02 (2006.01) A61K 39/395 (2006.01) C07H 21/00 (2006.01) C07K 14/20 (2006.01) C07K 16/12 (2006.01) G01N 33/569 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2190999

An antigenic preparation is provided which contains a 63 Kd outer membrane protein from Leptospira which can be used immunologically as a vaccine for leptospirosis caused by this organism. Also provided in the invention are polynucleotides encoding the protein and antibodies which bind the protein which are useful in the diagnosis of leptospirosis.

L'invention concerne une préparation antigénique contenant une protéine de membrane externe de 63 Kd provenant de l'organisme Leptospira, qui peut être utilisée à des fins immunologiques comme vaccin contre la leptospirose causée par cet organisme. L'invention se rapporte également à des polynucléotides codant cette protéine, ainsi qu'à des anticorps qui lient la protéine et qui peuvent être utilisés pour le diagnostic de la leptospirose.

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