C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/31 (2006.01) A61K 31/70 (2006.01) A61K 39/02 (2006.01) A61K 48/00 (2006.01) C07K 14/195 (2006.01) C12N 1/21 (2006.01) C12N 9/52 (2006.01) C12N 15/57 (2006.01) C12Q 1/68 (2006.01) G01N 33/569 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01)
Patent
CA 2206664
DNA fragments from Porphyromonas gingivalis which express hemagglutinin/proteases that elicit anti-P. gingivalis immunologic responses are described. Microorganisms, genetically modified to express P. gingivalis antigens, are provided. Also disclosed are probes, vaccines, and monoclonal antibodies for the detection and prevention of periodontal disease.
La présente invention concerne des fragments d'ADN de Porphyromonas gingivalis qui expriment des hémagglutinine/protéases qui provoquent des réponses immunologiques anti P. gingivalis. Elle concerne également des microorganismes modifiés génétiquement afin d'exprimer des antigènes P. gingivalis. Enfin, cette invention concerne des sondes, des vaccins et des anticorps monoclonaux destinés à la détection et à la prévention de paradontopathie.
Han Naiming
Lantz Marilyn
Lepine Guylaine
Patti Joseph M.
Progulske-Fox Ann
Macrae & Co.
Uab Research Foundation
University Of Florida
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