Clonidine assay

A - Human Necessities – 61 – K

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167/129, 167/139

A61K 39/00 (2006.01) C07D 233/50 (2006.01) G01N 33/531 (2006.01) G01N 33/539 (2006.01)

Patent

CA 1096305

RAN 4093/29 Case Docket No. 5352 CLONIDINE ASSAY Abstract A sensitive immunoassay for clonidine, 2-(2,6-dichloroanilino)-2-imidazoline hydrochloride is described. To prepare the clonidine selective antiserum, an antigen is made comprising 4-[[6-[2,4-dichloro-3-(4,5-dihydro-1H-imidazol-2-yl)amino] hydroxy- phenyl] azo] benzoic acid covalently bonded to an immunogenic carrier material through a peptide bond formed from said carboxyl group and amino groups contained in said immunogenic carrier material and the antigen is injected into a suitable host animal to elicit the desired antiserum.

285870

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