Cloning and characterisation of novel mammalian peptidases

Details Cloning and characterisation of novel mammalian peptidases Cloning and characterisation of novel mammalian peptidases

C - Chemistry, Metallurgy

12

N

C12N 15/52 (2006.01) A01K 67/027 (2006.01) A61K 31/70 (2006.01) A61K 38/43 (2006.01) C12N 5/10 (2006.01) C12N 9/64 (2006.01) C12Q 1/37 (2006.01) C12Q 1/68 (2006.01) G01N 33/50 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2337362

There is disclosed a cDNA molecule encoding human NAALAD-ases designated herein as L, II and IV and having the amino acid sequences illustrated in Figures 1, 3, 4 and 5. The NAALAD-ases themselves also form part of the invention. Further provided are expression vectors incorporating the cDNA molecules suitable for transforming a cell, tissue or organism.

On décrit une nouvelle molécule d'ADNc qui code les dipeptidases acides à liaison alpha N-acétylées appelées NAALAD-ases désignées L, II et IV et qui contient les séquences d'acides aminés présentées dans les figures 1, 3, 4 et 5. Les NAALAD-ases elles-mêmes font partie de l'invention. On décrit également des vecteurs d'expression qui contiennent les molécules d'ADNc appropriées pour transformer une cellule, un tissu ou un organisme.

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