Cloning and expression of a novel 5-ht4 receptor

C - Chemistry – Metallurgy – 12 – N

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C12N 15/12 (2006.01) A61K 38/17 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01) C12N 5/10 (2006.01) G01N 33/50 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2376389

There is disclosed an isolated or substantially pure form of a nucleic acid molecule encoding a human 5-HT4(h) receptor, which 5-HT4(h) receptor preferably comprises the sequence illustrated in Figure 1b. Also provided by the invention are expression vectors incorporating said nucleic acid molecule in addition to transgenic cells, tissues or organisms transfected with the nucleic acid molecule.

L'invention concerne une forme isolée ou sensiblement pure d'une molécule d'acide nucléique codant pour un récepteur 5-HT¿4(h)? qui comprend de préférence la séquence illustrée dans la figure 1b. L'invention porte également sur des vecteurs d'expression incorporant ladite molécule d'acide nucléique, et sur des cellules, tissus ou organismes transgéniques transfectés avec la molécule d'acide nucléique.

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