Cloning and expression of .beta.app-c100 receptor (c100-r)

Details Cloning and expression of .beta.app-c100 receptor (c100-r) Cloning and expression of .beta.app-c100 receptor (c100-r)

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61K 38/17 (2006.01) A61K 39/395 (2006.01) C07H 21/00 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01) C07K 19/00 (2006.01) C12N 9/12 (2006.01) C12N 15/62 (2006.01) C12Q 1/48 (2006.01) C12Q 1/68 (2006.01) G01N 33/566 (2006.01)

Patent

CA 2238007

The present invention relates to the cloning of .beta.APP-C100 receptor (C100- R), and genetically engineered host cells which express the C100-R. Such engineered cells may be used to evaluate and screen drugs and analogs of .beta.-APP involved in Alzheimer's Disease.

L'invention concerne le clonage du récepteur de .beta.APP-C100 (C100-R), ainsi que des cellules hôtes mises au point par génie génétique et exprimant le C100-R. Lesdites cellules peuvent être utilisées pour évaluer et cribler des médicaments et des analogues de .beta.-APP impliquée dans la maladie d'Alzheimer.

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