C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/13 (2006.01) A61K 39/395 (2006.01) C07K 16/24 (2006.01) C07K 16/46 (2006.01) C12N 5/10 (2006.01) C12N 5/26 (2006.01) C12P 21/08 (2006.01) G01N 33/531 (2006.01) G01N 33/577 (2006.01) G01N 33/74 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2130436
Monoclonal antibodies are provided which are specific for human interleukin-4. Also provided are complementary DNAs which-encode the heavy and light chain variable regions of such monoclonal antibodies and complementarily determining regions from such DNAs; and kits and methods for detecting; measuring and immunopurifying human intecleukin-4; and for blocking the biological activity of human interleukin-4.
L'invention concerne des anticorps monoclonaux spécifiques de l'interleukine-4 humaine. L'invention concerne aussi des ADN complémentaires qui codent les régions variables à chaînes légères et lourdes desdits anticorps et les régions déterminantes de complémentarité de ces ADN. Enfin l'invention concerne les nécessaires et procédés permettant de détecter, mesurer et immuno-purifier l'interleukin-4 humaine, ainsi que de bloquer l'activité biologique de cette interleukine-4.
Abrams John S.
Dalie Barbara
Le Hung V.
Miller Kenneth
Murgolo Nicholas J.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
Schering Corporation
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