Cloning and identification of a two component signal...

Details Cloning and identification of a two component signal... Cloning and identification of a two component signal...

C - Chemistry, Metallurgy

12

N

C12N 15/31 (2006.01) C07H 21/04 (2006.01) C07K 14/195 (2006.01) C12N 1/21 (2006.01) C12N 9/12 (2006.01) C12N 15/52 (2006.01) C12N 15/54 (2006.01)

Patent

CA 2116422

CLONING AND IDENTIFICATION OF A TWO COMPONENT SIGNAL TRANSDUCING REGULATORY SYSTEM FROM BACTEROIDES FRAGILIS Abstract of the Disclosure This invention relates to a purified isolated DNA fragment of Bacteroides fragilis comprising a sequence for an operon containing two genes designated rprX and rprY. These genes encode two signal transducing regulatory proteins designated RprX and RprY. This invention further relates to the proteins RprX and RprY encoded by the operon. RprX and RprY affect the normal regulation of OmpF by OmpR and EnvZ.

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