Cloning and sequencing of the gene which codes for a new...

Details Cloning and sequencing of the gene which codes for a new... Cloning and sequencing of the gene which codes for a new...

C - Chemistry, Metallurgy

12

N

530/13, 167/137,

C12N 15/31 (2006.01) A61K 39/10 (2006.01) C07K 14/235 (2006.01) C12N 1/19 (2006.01) C12N 1/21 (2006.01) A61K 39/00 (2006.01)

Patent

CA 1338632

The cloning and sequencing of the gene which codes for a new pilinic subunit of Bordetella pertussis are described. The aminoacid sequence of the mature subunit, deduced from its necleotide sequence, is similar but not identical to that of the known pilins 2, 3 and 6. Polypeptides having the aminoacid sequence of the mature pilinic subunit or of regions thereof are particularly useful for the development of synthetic acellular vaccines against pertussis.

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