Cloning and sequencing of the major outer capsid...

Details Cloning and sequencing of the major outer capsid... Cloning and sequencing of the major outer capsid...

C - Chemistry, Metallurgy

12

N

167/130, 530/7.0

C12N 15/46 (2006.01) A61K 39/15 (2006.01) C07K 14/14 (2006.01) A61K 39/00 (2006.01)

Patent

CA 1339735

This invention provides a human rotavirus gene and a cloned human rotavirus gene and the dsRNA gene segment coding for the major outer capsid glycoprotein of a human rotavirus. The human rotavirus may be Hu/Australia/5/77 (serotype 2), a DNA copy or a clone thereof, or a vector or a host cell containing the same, or peptide sequences obtained therefrom. This may encompass vectors such as plasmids obtained therefrom, or host cells that contain them. From specific portions of cloned genes provided by the invention, comprising amino acid sequences, anti-sera and anti-bodies may be prepared, primarily intended to counter infantile gastroenteritis.

480251

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