C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01) C07K 14/435 (2006.01) C07K 14/82 (2006.01) C12N 9/16 (2006.01) C12N 15/10 (2006.01) C12N 15/12 (2006.01) C12N 15/55 (2006.01) C12N 15/81 (2006.01)
Patent
CA 2080920
Disclosed are methods for detecting mammalian genes encoding proteins which can function in microorganisms, particu- larly yeast, to modify, complement, or suppress a genetic defect associated with an identifiable phenotypic alteration or character- istic in the microorganism. Disclosed also are mamalian DNA sequences cloned bythe above method, as well as polypeptide pro- ducts of the expression of the DNA sequences in procaryotic or eucaryotic host cells and antibody substances which are specifically immunoreactive with said expression products. More specifically, the present invention methods for cloning mam- malian genes which encode products which modify, complement or suppress a genetic defect in a biochemical pathway in which cAMP participates or in a biochemical pathway which is controlled, directly or indirectly, by an RAS protein, to products (RNA, proteins) encoded by the mammalian genes cloned in this manner, and to antibodies which can bind the encoded proteins.
Colicelli John J.
Wigler Michael H.
Cold Spring Harbor Laboratory
Smart & Biggar
LandOfFree
Cloning by complementation and related processes does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Cloning by complementation and related processes, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Cloning by complementation and related processes will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1900520