A - Human Necessities – 01 – K
Patent
A - Human Necessities
01
K
A01K 67/00 (2006.01) A01K 67/027 (2006.01) C12N 5/00 (2006.01) C12N 15/00 (2006.01) C12N 15/87 (2006.01)
Patent
CA 2381124
An improved method of nuclear transfer involving the transplantation of donor differentiated pig cell nuclei into enucleated pig oocytes is provided. The resultant nuclear transfer units are useful for multiplication of genotypes and transgenic genotypes by the production of fetuses and offspring. Production of genetically engineered or transgenic pig embryos, fetuses and offspring is facilitated by the present method since the differentiated cell source of the donor nuclei can be genetically modified and clonally propagated.
L'invention concerne un procédé amélioré de transfert nucléaire impliquant la transplantation de noyaux de cellules de porcs différenciées de donneurs dans des ovocytes de porcs énucléés. Les unités de transfert nucléaire qui en résultent servent à la multiplication de génotypes et de génotypes transgéniques par production de foetus et de progéniture. Ce procédé facilite la production d'embryons, de foetus et de progéniture de porcs génétiquement modifiés ou transgéniques, puisque la source de cellules différenciées du noyau donneur peut être génétiquement modifiée et propagée par clonage.
Cibelli Jose
Golueke Paul
Robl James
Stice Steven L.
As Represented By Its Amherst Campus University Of Massachusetts A. Public Institution Of Higher Educ
Gowling Lafleur Henderson Llp
LandOfFree
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