C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/37 (2006.01) C12N 5/10 (2006.01) C12Q 1/02 (2006.01) C07K 14/33 (2006.01) C12N 9/52 (2006.01)
Patent
CA 2605160
Compositions useful for detecting Clostridial toxin activity comprising a cell that contains an exogenous Clostridial toxin substrate comprises a fluorescent member, a membrane targeting domain and a Clostridial toxin recognition sequence comprising a cleavage site, where the cleavage site intervenes between said fluorescent member and said membrane localization domain and methods useful for determining Clostridial toxin activity using such Clostridial toxin substrates.
La présente invention concerne des compositions utilisées pour détecter l'activité d'une toxine clostridiale, lesquelles compositions comprennent une cellule contenant un substrat de toxine clostridiale exogène qui présente un élément fluorescent, un domaine de ciblage de membrane et une séquence de reconnaissance de toxine clostridiale comportant un site de clivage. Le site de clivage intervient entre l'élément fluorescent et le domaine de localisation de membrane. Cette invention concerne également des procédés permettant de déterminer l'activité d'une toxine clostridiale au moyen de tels substrats de toxine clostridiale.
Aoki Kei Roger
Fernandez-Salas Ester
Steward Lance E.
Allergan Inc.
Gowling Lafleur Henderson Llp
LandOfFree
Clostridial toxin activity assays does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Clostridial toxin activity assays, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Clostridial toxin activity assays will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1811452