Clostridial toxin disease therapy

Details Clostridial toxin disease therapy Clostridial toxin disease therapy

C - Chemistry, Metallurgy

12

P

C12P 21/00 (2006.01) A61K 39/08 (2006.01) A61K 39/42 (2006.01) C07K 14/33 (2006.01) C07K 16/02 (2006.01) C07K 16/12 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2150935

The present invention includes methods and compositions for treating humans and other animals intoxicated with at least one bacterial toxin by administration of antitoxin. The figure illustrates a plasmid encoding such a toxin, Clostridium difficile toxin A. In particular, the antitoxin directed against these toxcins is produced in an avian species. The avian antitoxin is designed so as to be orally administerable in therapeutic amounts and may be in any form (i.e., a solid or aqueous solution).

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