Clotting factor-fc chimeric proteins to treat hemophilia

Details Clotting factor-fc chimeric proteins to treat hemophilia Clotting factor-fc chimeric proteins to treat hemophilia

C - Chemistry, Metallurgy

12

N

C12N 15/62 (2006.01) A61K 38/36 (2006.01) A61K 39/395 (2006.01) A61P 7/04 (2006.01) C07K 14/745 (2006.01) C07K 16/28 (2006.01) C07K 19/00 (2006.01) C12N 15/12 (2006.01) C12N 15/13 (2006.01) C12P 21/02 (2006.01) C12P 21/08 (2006.01)

Patent

CA 2522859

The invention relates to a chimeric protein comprising at least one clotting factor and at least a portion of an immunoglobulin constant region. The invention relates to a method of treating a hemostatic disorder comprising administering a therapeutically effective amount of a chimeric protein wherein the chimeric protein comprises at least one clotting factor and at least a portion of an immunoglobulin constant region.

L'invention concerne une protéine chimérique comprenant au moins un facteur de coagulation et au moins une partie d'une région constante d'une immunoglobuline. L'invention concerne une méthode de traitement d'un trouble hémostatique consistant à administrer une quantité thérapeutiquement efficace d'une protéine chimérique, ladite protéine chimérique comprenant au moins un facteur de coagulation et au moins une partie d'une région constante d'une immunoglobuline.

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