C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/525 (2006.01) A01K 67/027 (2006.01) A61K 38/17 (2006.01) A61K 38/19 (2006.01) A61K 48/00 (2006.01) C07K 14/47 (2006.01) C12N 15/62 (2006.01) C12Q 1/68 (2006.01)
Patent
CA 2538695
This invention relates to the novel protein, termed INSP163, herein identified as a secreted protein containing a jelly-roll fold, in particular, as a member of the TNF (tumor necrosis factor)-like family of cytokines, specifically as a Clq-like protein and to the use of this protein and nucleic acid sequence from the encoding gene in the diagnosis, prevention and treatment of disease.
La présente invention concerne une nouvelle protéine appelée INSP163, identifiée en tant que protéine de sécrétion contenant un repli roulé, en particulier en tant que membre de la famille des cytokines, analogue au facteur TNF (tumor necrosis factor / facteur de nécrose tumorale), en particulier en tant que protéine analogue à c1q. L'invention a également pour objet l'utilisation de cette protéine et d'une séquence d'acide nucléique du gène codant pour celle-ci, dans le cadre du diagnostic, de la prévention et du traitement de maladies.
Bienkowska Jadwiga
Fagan Richard Joseph
Fitzgerald Stephen Noel
Power Christine
Yorke Melanie
Ares Trading S.a.
Kirby Eades Gale Baker
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