Cluster clearing agents

Details Cluster clearing agents Cluster clearing agents

A - Human Necessities

61

K

A61K 31/70 (2006.01) A61K 47/48 (2006.01) C07H 15/26 (2006.01)

Patent

CA 2257363

Cluster clearing agents (CCAs) and the use thereof are discussed. CCAs are composed of a hepatic clearance directing moiety which directs the biodistribution of a CCA-containing construct to hepatic clearance; and a binding moiety which mediates binding of the CCA to a compound for which rapid hepatic clearance is desired.

L'invention concerne des agents de suppression des amas et leur utilisation. Ces agents se composent d'une fraction assurant la clairance hépatique qui dirige la biodistribution d'un produit de recombinaison contenant des agents de suppression des amas, et une fraction de liaison qui assure la liaison de ces agents à un composé pour lequel une clairance hépatique rapide doit être assurée.

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