C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01) C12N 5/10 (2006.01) C12N 15/63 (2006.01) C12Q 1/68 (2006.01) G01N 33/50 (2006.01)
Patent
CA 2418848
The invention provides isolated nucleic acid and amino acid sequences of CNG2B, antibodies to CNG2B, methods of detecting CNG2B, and methods of screening for modulators of cyclic nucleotide-gated ion channels using biologically active CNG2B. The invention further provides, in a computer system, a method of screening for mutations of human CNG2B genes as well as a method for identifying a three-dimensional structure of human CNG2B polypeptides.
L'invention concerne un acide nucléique isolé et des séquences d'acides aminés de CNG2B, des anticorps dirigés contre CNG2B, des méthodes de détection de CNG2B, ainsi que des méthodes de criblage de modulateurs de canaux ioniques dépendant de nucléotides cycliques à l'aide de CNG2B biologiquement actif. L'invention concerne également, dans un système informatique, une méthode de criblage de mutations des gènes CNG2B humains ainsi qu'une méthode d'identification d'une structure tridimensionnelle des polypeptides CNG2B humains.
Creech Christopher D.
Jegla Timothy James
Fetherstonhaugh & Co.
Icagen Incorporated
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