Cns neuroregenerative compositions and methods of use

A - Human Necessities – 61 – K

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Details

A61K 38/18 (2006.01) A01K 67/027 (2006.01) A61K 9/00 (2006.01) A61K 48/00 (2006.01) C07K 14/475 (2006.01) C12N 5/10 (2006.01) C12N 15/85 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2293492

The invention features a method for promoting neural growth in vivo in the mammalian central nervous system by delivering a composition comprising a combination of neurotrophins to promote neural growth. Active fragments, cognates, congeners, mimics, analogs, secreting cells and soluble molecules thereof, and DNA molecules, vectors and transformed cells capable of expressing them are similarly utilizable in the methods of the instant invention.

Cette invention se rapporte à un procédé permettant de promouvoir la croissance neurale in vivo dans le système nerveux central des mammifères, par administration d'une composition contenant une combinaison de neurotrophines propres à promouvoir la croissance neurale. Des fragments actifs, des cognats, des congénères, des mimétiques, des analogues, des cellules sécrétrices et des molécules solubles de cette composition, ainsi que des molécules d'ADN, des vecteurs et des cellules transformées capables d'exprimer ces derniers sont utilisables de la même manière dans les procédés faisant l'objet de cette invention.

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