Co-crystals and pharmaceutical compositions comprising the same

Details Co-crystals and pharmaceutical compositions comprising the same Co-crystals and pharmaceutical compositions comprising the same

C - Chemistry, Metallurgy

07

D

C07D 403/12 (2006.01) A61K 31/454 (2006.01) A61P 1/16 (2006.01)

Patent

CA 2704284

The invention relates to co-crystals and compositions each comprising VX-950 and a co-crystal former selected from the group consisting of 3-methoxy-4-hydroxybenzoic acid, 2,4- dihydroxybenzoic acid, and 2,5-dihydroxybenzoic acid. Also within the scope of this invention are methods of making and using the same.

L'invention porte sur des co-cristaux et des compositions comportant chacune VX-950 et un agent de génération de co-cristal choisi dans le groupe constitué par l'acide 3-méthoxy-4-hydroxybenzoïque, l'acide 2,4-dihydrobenzoïque et l'acide 2,5-dihydroxibenzoïque. L'invention porte également sur des procédés de fabrication et d'utilisation de ces compositions.

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